Courses
The total of four required courses can be selected from those marked
with an asterisk (*) in the list of courses. below. Four additional graded
electives must be taken, one of which may be a reading course. They can
be selected according to the student’s interests and the availability
of courses.
31000. Fundamentals in Molecular Biology*
Storb, Staley
The course covers nucleic acid structure and DNA topology, recombinant
DNA technology, DNA replication, DNA damage, mutagenesis and repair, Transposons
and site-specific recombination, prokaryotic and eukaryotic transcription
and its regulation, RNA structure, splicing and catalytic RNAs and protein
synthesis.
31200. Molecular Biology I*
Rothman-Denes
Nucleic acid structure; mechanisms of transcription, replication, and
recombination and their regulation in prokaryotes and eukaryotes.
31300. Molecular Biology II*
Singh, Staley
Analysis of regulatory pathways and mechanisms involved in the control
of eukaryotic gene activity.
31400. General Principles of Genetic Analysis*
Bishop, Lahn
Coverage of the fundamental tools of genetic analysis as used to study
biological phenomena. Topics include genetic exchange in prokaryotes,
eukaryotes, and their viruses and plasmids; principles of transformation;
analysis of gene function.
31500. Genetic Mechanisms*
Bishop, Frank
Advanced coverage of genetic mechanisms, including genetic analysis of
molecular mechanisms in meiosis and mitosis; recombination mechanisms;
and genetics of transposons.
31600. Cell Biology*
Turkewitz, Glick
A lecture/discussion course on fundamentals of protein synthesis and translocation,
protein and membrane sorting and transport, organelle biogenesis, and
the cytoskeleton.
31700. Advanced Cell Biology*
Lamppa
Chromatin structure and its role in transcription, communication between
nucleus and cytoplasm, translation, protein folding and assembly, molecular
chaperones, elements of signal transduction, homeostasis, growth control
and the cell cycle, cytoarchitecture, cell adhesion and migration.
31900. Introduction to Research in MGCB
Staff
Lectures on current research by departmental faculty and other invited
speakers. A required course for all first-year graduate students in MGCB.
34300. Principles and Practices of Electron Microscopy
Josephs
This course deals with the principles involved in obtaining electron micrographs
of biological specimens. Preparation techniques and analytical procedures
will be offered at an individualized level.
34600. Animal Viruses (=Virol 34600)
Roizman
An advanced lecture/seminar course on special topics in animal virology.
Not given every year.
35400. Advanced Developmental Biology
Ferguson, Malamy
This course provides an overview of the fundamental questions of developmental
biology, presenting both the classical embryological experiments that
defined these questions, and the modern molecular and genetic experiments
that have been employed to try to reach mechanistic answers to these questions.
The first portion of the course will focus on the mechanism of embryonic
axis formation in a variety of organisms; the second part of the course
will explore selected topics in the field.
35500. Developmental Genetics of Model Systems
Ferguson, Du, Greenberg
Lectures and discussions on the use of genetics as a tool to understand
basic mechanisms in animal development. The organisms studied include
the nematode C. elegans, the fruit fly Drosophila melanogaster, and the
plant Arabidopsis thaliana.
35600. Vertebrate Development
Prince, Millen
Lectures and discussions on early development in Zebrafish, Xenopus, chick,
and mouse. Topics will include vertebrate head and trunk organizer, Hox
genes, somitogenesis, organogenesis, neural patterning, neural crest development,
and stem cells.
This list was last revised on 9/2/2003.
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