PROGRAMMATIC CORE
MICR 33000. Molecular Genetic Analysis of Bacteriophage. Examines a series
of bacteriophage that have been instrumental in our understanding of genetics
and molecular biology, with an emphasis on their properties and the methods
for which they are used in current and potential biological studies and
in biotechnology.
Casadaban. Spring.
MICR 34000 Bacterial Pathogenesis. Molecular basis of bacterial pathogenesis
of human, animal and plant bacteria, their infection strategies and molecular
mechanisms of causing disease.
Schneewind. Winter.
MICR 34200 Microbial Genomes.
Examines the information available from complete bacterial genome sequences.
It addresses the usefulness of sequence databases and bioinformatics for
answering questions of functional and comparative genomics. The genome
sequences serve as the basis for addressing topics in microbiology (e.g.
metabolic diversity, intercellular communication, cellular differentiation,
pathogenicity, vaccine development, and bacterial evolution).
Shaprio. Spring.
MICR 34600 Eukaryotic Viruses.
This course describes the viruses that infect animal and human cells,
their structure and assembly pathways.
Roizman, Pilipenko. Spring.
MICR 39000 Introduction to Experimental Microbiology.
This seminar series with nine presentations by faculty invited from outside
institutions during the Autumn and Winter Quarters. A required reading
discussion session accompanies the seminar series.
Schneewind. Autumn, Winter.
MICR 40000 Microbiology Data Club.
All graduate students, postdoctoral fellows and honors undergraduate students
of the Committee on Microbiology present their research in a central forum,
once each year. This course provides a forum to ensure continued progress
of graduate students in their thesis projects, interaction between Committee
on Microbiology scientists and development of novel ideas and avenues
of research.
Schneewind. Autumn, Winter.
Cell Biology
MGCB 31600* Cell Biology I.
Lecture/discussion course on fundamentals of protein synthesis and translocation,
protein and membrane sorting and transport, organelle biogenesis, and
the cytoskeleton.
Turkewitz, Glick. Autumn.
MGCB 31700 Advanced Cell Biology. Chromatin structure and its role in
transcription, communication between nucleus and cytoplasm, translation,
protein folding and assembly, molecular chaperones, elements of signal
transduction, homeostasis, growth control and the cell cycle, cytoarchitecture,
cell adhesion and migration.
Mueller, Lamppa. Winter.
Genetics
GENE 31400 General Principles of Genetic Analysis.
Coverage of the fundamental tools of genetic analysis as used to study
biological phenomena. Topics include genetic exchanges in prokaryotes,
eukaryotes, and their viruses and plasmids; principles of transformation;
analysis of gene function.
Ferguson, Preuss, Lahn. Autumn.
GENE 31500 Genetic Mechanisms. Advanced coverage of genetic mechanisms
involved in genome stability and rearrangement. Topics include genetics
of transposons, site-specific recombination, gene conversion, reciprocal
crossing over, and plasmid and chromosome segregation.
Esposito, Frank, Bishop. Winter.
Molecular Biology
MGCB 31000 Fundamentals in Molecular Biology.
The course covers nucleic acid structure and DNA topology, recombinant
DNA technology DNA replication, DNA damage, mutagenesis and repair, transposons
and site-specific recombination. Prokaryotic and eukaryotic transcription
and its regulation, RNA structure, splicing and catalytic RNAs, protein
synthesis, and chromatin.
Storb, Staley. Winter.
MGCB 31200 * Molecular Biology I.
Nucleic acid structure; mechanisms of transcription, replication, and
recombination and their regulation in prokaryotes and eukaryotes. Consent
of instructor.
Rothman-Denes. Winter.
MGCB 31300 Molecular Biology II.
Topics include transcription and post-transcription, changes in chromatin
structure during gene activation, tissue- and developmental-specific transcription
regulators, and post-transcriptional regulation of gene expression. Prereq:
MGCB 31200 or consent of instructor.
Singh, Staley. Spring.
This list was last revised on 9/08/2003.
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