Courses in the Committee on Medical Physics (Radiology)

Courses

MPHY 34200. Practicum in the Physics of Medical Imaging I
Jiang, La Rivière, Karczmar
This laboratory course is designed to enhance students’ understanding of the theories presented in the course Physics of Medical Imaging I and to acquaint students with the operation of a diagnostic radiology clinic. Students are expected to gain practical experience in the clinical use of diagnostic x-ray generators, screen-film combinations, digital acquisition systems and their image processing techniques, and in research on magnetic resonance imaging (MRI) and computer-aided diagnosis (CAD).

MPHY 34300. Practicum in the Physics of Medical Imaging II
O’Brien-Penney, Pan, Pelizzari
This laboratory course is designed to familiarize the medical physics student with certain equipment and procedures in diagnostic radiology, with emphasis on nuclear medicine, ultrasonic and x-ray (helical) computed tomographic imaging. A special project will be part of the course requirements.


MPHY 34400. Practicum in the Physics of Radiation Therapy
Reft and staff
This course combines lectures and intensive hands-on experiments. It includes an introduction to thermoluminescent, film and ionization chamber dosimetry, Monte Carlo radiation transport simulation and intensity-modulated radiotherapy. Training in data acquisition, error analysis, experimental techniques and the safe handling of sealed radioactive sources will be included.
Prereq: MPHY 35100 or consent of instructor.

MPHY 34900. Mathematics for Medical Physics
Giger, Metz, Pan
This is a required course in the Graduate Programs in Medical Physics. This first quarter course surveys the mathematics necessary for the understanding of physical phenomena and applications in medical imaging and medical physics, which will be presented later to the students in their graduate coursework. The course covers linear algebra, Fourier analysis and transfer function analysis, Radon transforms, probability theory and stochastic processes, estimation theory, ROC analysis, and signal detection theory. Although each student is assumed to have been acquainted previously with at least some of these topics, no specific mathematical background beyond that of a strong undergraduate physics major is prerequisite.

MPHY 35000. Interactions of Ionizing Radiation with Matter
Roeske, Armato
Interaction of electromagnetic and particulate radiation with matter. Special emphasis on energy absorption, detection, control, and production, and on their relation to medical applications. Prereq: Physics, 22700, 23700
or equivalent.

MPHY 35100. Physics of Radiation Therapy
Pelizzari and staff
This course covers aspects of radiation physics necessary for understanding modern radiation therapy. Rigorous theoretical foundations of physical dose calculation for megavoltage energy photons and electrons, biological predictions of therapy outcomes, and brachytherapy are presented. Methods of modeling and implementing radiation therapy treatment planning, evaluation, and delivery are described. Emphasis is placed on current developments in the field including intensity modulated radiation therapy. The course is intended to provide comprehensive knowledge of radiation therapy physics enabling the student to grasp current research in the field. Prereq: MPHY 35000 or consent of instructor.

MPHY 35300. Medical Image Reconstruction
Chen, Pan
Image reconstruction from projections, focusing on medical applications to X-ray computed tomography (CT), positron emission tomography (PET), and single-photon attenuation, scattered radiation involved in these imaging methods and their effects.

MPHY 35400. Health Physics
Pelizzari and Staff
The problems of the protection of active workers and the general public from unnecessary and excessive exposure to penetrating radiation. Prereq: MPHY 35000, 35100.

MPHY 35600. Anatomical Structure of the Body
Giger and Staff
Gross anatomy of the human body with correlation to medical images. In addition, radiographic, tomographic, radioisotope, ultrasound, and magnetic resonance images are used to present normal and pathological states of the anatomy. Designed to educate graduate and medical students with primary backgrounds in physics and engineering.

MPHY35800. Biomedical Applications of Magnetic Resonance
Karczmar and Staff
Introduction to the physics of magnetic resonance, magnetic resonance methodology, and the applications of these methods to a variety of biomedical problems, including determination of protein structure by MR, metabolic imaging, anatomic imaging, solid state imaging, electron spin resonance,
measurement of blood flow and perfusion, and effects of contrast agents. Prereq:MPHY 38700 or consent of instructor.

MPHY 35900. Cancer and Radiation Biology
Grdina
This course provides students with an overview of the biology of cancer and of the current methods used to diagnose and treat the disease. Lectures from faculty throughout the Biological Sciences Division include presentations on cancer incidence and mortality, cancer prevention, a molecular biology perspective, the role of genetic markers, the imaging of pathology, methods of treatment (radiation, chemotherapy) and prognosis, and the role of medical ethics and patient care. The course is primarily for medical physics students.

MPHY 37000. Advanced Computing for Imaging Applications
Chen, Pelizzari
Introduces new computing concepts and current computer technologies, particularly the various uses of interpreted languages.

MPHY 37800. Basic Radiation Biology
Grdina and Staff
A series of lectures related to the effects of ionizing radiation upon living cell, tissues, organs, organ systems, animals and man, either singly or in populations. The purpose is to acquaint medical students, BSD graduate students, and physicians with the nature and consequences of the interaction of ionizing radiations with living matter.

MPHY 38200. Transfer Function Analysis of Radiologic Imaging Systems
Metz
Development of mathematical techniques useful in analyzing spatial resolution in radiography, nuclear medicine and computed tomography. Topics include: linear shift-invariant system, Fourier series and Fourier transforms, image reconstruction in computed tomography and methodology for measuring system transfer functions. Prereq: MPHY 38600 or 38700; consent of instructor.

MPHY 38300. Analysis of Noise in Radiologic Imaging
Metz
Development of mathematical techniques useful for analysis of statistical fluctuations in radiologic imaging, with applications in radiography and nuclear imaging. Topics include: probability, random variables, stochastic processes, power spectra, transfer of noise through linear shift-invariant systems, and imaging processing. Prereq: MPHY 38600 and 38700 or consent of instructor.

MPHY 38600. Physics of Medical Imaging I
Nishikawa, La Riviere, Karczmar
This is an introductory course to the basic elements of x-ray imaging and magnetic resonance imaging and spectroscopy. Topics covered on x-ray imaging include x-ray production, image formation, analog and digital detectors, physical measures of image quality, fluoroscopy, and computer-aided diagnosis. Topics covered on magnetic resonance imaging include nuclear magnetic resonance, relaxation times, pulse sequences and spectroscopy.

MPHY 38700. Physics of Medical Imaging II
Pan, Kao,Chen, O’Brien-Penney
The course covers the fundamentals of nuclear medicine, ultrasonic, and x-ray computed tomographic imaging. Topics include: physics, mathematics, and statistics of image formation in SPECT, PET, conventional ultrasound, ultrasonic diffraction tomography, conventional and helical computed tomography. Functional imaging and compartmental analysis are also covered.

MPHY 39100. Physics of Mammography
Nishikawa and Staff
This is an advanced course designed to give students an in-depth understanding of the application of basic medical physics concepts and principles to the problem of breast cancer detection using mammography. While focusing on mammography, students will examine how image quality is affected by x-ray generation and the acquisition and display of the image. Topics covered will include radiographic properties of breast tissue; image quality requirements for breast imaging; relationship between x-ray equipment and image quality; dosimetry; risk/benefit analysis as applied to screening; digital mammography (hardware, image processing, and computer-aided diagnosis). This course will be offered as a reading course with a weekly discussion on the assigned reading material.

MPHY 39300. Clinical Physics in Positron Emission Tomography (PET)
Chen and Staff
This course is designed to provide in-depth experience in the clinical physics of PET. It focuses on PET technology and PET applications. Students learn PET instrumentation and procedures for operation and
calibration of PET systems, computer and networking facilities, quality assurance programs, major PET protocols, and data and image analysis methods.

MPHY 39400. Chemistry of Diagnostic Agents
Karczmar
This course introduces the students to chemical and biochemical principles involved in the design, development and use of radiopharmaceuticals and contrast agents for medical applications in single photon emission computed tomography, positron emission tomography, magnetic resonance imaging and spectroscopy,
computed tomography, and ultrasound.

MPHY 42000 Research in the Physics of Nuclear Medicine
Chen, Pan, Kao, La Riviere and staff
Possible research topics include the development of methods to improve diagnostic accuracy; development of SPECT and PET; development of image reconstruction techniques; analysis and evaluation of imaging system components; and joint physical/clinical studies of new techniques in nuclear medicine. Prereq: Consent of instructor.

MPHY 42100. Research in the Physics of Diagnostic Radiology
Doi, Giger, Nishikawa, Metz, Yoshida, Armato, Jiang and Staff
Possible research topics include the development of methods to improve diagnostic accuracy and/or to reduce patient radiation exposure; development of computerized methods for the interpretation of image data; analysis and evaluation of imaging system components; and joint physical/clinical studies of new techniques in diagnostic radiology. Prereq: Consent of instructor.

MPHY 42200 Research in the Physics of Radiation Therapy
Pelizzari, Roeske, and staff
Possible research topics include the development of methods to improve methods of radiation therapy; investigation of IMRT fields for dynamic dose delivery; megavoltage CT; 3D reconstruction of brachytherapy sources from CT localizer images and joint physical/clinical studies of new techniques in radiation therapy. Prereq: Consent of instructor.

MPHY 42300. Principles of Magnetic Resonance Imaging and Spectroscopy
Levin, Karczmar
Reading course on the physical and mathematical principles of magnetic resonance image formation and post-processing. Methods of acquiring localized biochemical spectra in vivo as well as spectroscopic imaging are also discussed. Prereq: Consent of instructor.

 

This list was last revised on 12/18/2003.